王明轩，讲师

 

联系方式

办公地点：材料化学国家重点实验室C-409

电    话：025-58139433

邮    箱：mingxuanwang@njtech.edu.cn

 

教育背景

2007.09-2011.06  江南大学食品科学与工程，工学学士

2011.09-2017.12  江南大学食品科学，工学博士

2012.12-2015.12  美国维克森林大学生物化学系，联合培养博士

 

工作经历

2018.03-至今： 南京工业大学食品与轻工学院，讲师

 

研究方向

主要从事食品微生物学及蛋白质结构生物学相关领域科研工作。研究工作围绕微生物产功能多不饱和脂肪酸、产功能多肽的研究及应用展开。

 

基金项目

 

1. 国家自然科学青年基金：小白链霉菌聚二氨基丙酸合成关键酶的结构域功能与催化机制研究（31900030），2020.1-2022.12，主持。

2. 江苏省教育厅高校自然科学研究计划项目：聚二氨基丙酸生物合成关键酶的催化机制研究（19KJB530009），2019.9-2021.8，主持。

 

代表性论文

[1] Mingxuan Wang, Jian Xue, Junjie Ma, Xiaohai Feng, Hanjie Ying, Hong Xu*. Streptomyces lydicus M01 regulates soil microbial community and alleviates foliar disease caused by Alternaria alternate on cucumbers. Frontiers in Microbiology, 2020, 11(942)

[2] Mingxuan Wang, Junjie Ma, Zongqi Xu, Xiaohai Feng, Hong Xu*. First report of shoot blight on fragrant pear caused by Pantoea ananatis in China. Plant disease, 2019, 103(7): 1764-1764

[3] Mingxuan Wang, Haiqin Chen, Aisikaer Ailati, Wei Chen, Floyd H. Chilton, W. Todd Lowther*, Yong Q. Chen*. Substrate specificity and membrane topologies of the iron-containing, ω3 and ω6 desaturases from Mortierella alpina. Applied Microbiology and Biotechnology, 2018, 102(1): 211-223.

[4] Mingxuan Wang, Haiqin Chen*, Zhennan Gu, Hao Zhang, Wei Chen, Yong Q. Chen. ω3 fatty acid desaturases from microorganisms: structure, function, evolution, and biotechnological use. Applied Microbiology and Biotechnology, 2013, 97(24): 10255-10262.

[5] Mingxuan Wang, Jianxin Chen, Huaiyuan Zhang, Yuanda Song*. Molecular switch that controls the flux of linoleic acid into n-6 or n-3 polyunsaturated fatty acids in microorganisms. American Journal of Biochemistry and Biotechnology, 2014, 10(2): 105-115.

[6] Haiqin Chen, Zhennan Gu, Hao Zhang, Mingxuan Wang, Wei Chen, W. Todd Lowther, Yong Q Chen*. Expression and purification of integral membrane fatty acid desaturases. PLoS One, 2013, 8(3): e58139.

[7] Delei Xu, Rui Wang, Zhaoxian Xu, Zheng Xu, Sha Li, Mingxuan Wang, Xiaohai Feng, and Hong Xu*. Discovery of a short-chain ε-poly-L-lysine and its highly efficient production via synthetase swap strategy. Journal of Agricultural and Food Chemistry, 2019, 67, 5, 1453-1462.

[8] Yuanyuan Sha, Yatao Zhang, Yibin Qiu, Zongqi Xu, Sha Li, Xiaohai Feng, Mingxuan Wang, and Hong Xu*. Efficient biosynthesis of low-molecular-weight poly-γ-glutamic acid by stable overexpression of PgdS hydrolase in Bacillus amyloliquefaciens NB. Journal of Agricultural and Food Chemistry, 2019, 67, 1, 282–290.  

[9] 王明轩，陈海琴*，顾震南，陈卫，陈永泉. 高山被孢霉ATCC 32222中细胞色素b5还原酶I的克隆、表达和功能鉴定. 微生物学通报, 2016, 43(10): 2172−2178.

[10] 王明轩，陈海琴*，顾震南，陈卫，陈永泉. 高山被孢霉中Δ9脂肪酸脱饱和酶的表达、纯化和其细胞色素b5功能域的鉴定. 中国生物工程杂志, 2017, 37(3): 43-50.