- 阅读次数:
- 发布时间:2022-03-14
王银珠 副教授 硕导
联系方式
办公地点:尚德楼食品与轻工学院206
电话:025-58139426
电子邮箱:wangyz@njtech.edu.cn
教育与工作经历
2014-2018 南京大学 化学 博士
2018-2021 江苏科技大学 环境与化学工程学院 副教授
2021至今 南京工业大学 食品与轻工学院 副教授
研究领域
1. 电致化学发光技术用于核酸、蛋白质、细胞、微生物、益生菌等生物分子的传感检测;
2. 单颗粒电化学发光生物成像分析;
3. 电化学土壤修复、微生物修复;
基金项目
1. 国家自然科学基金面上项目,基于微流控芯片电泳-电致化学发光技术的食品中多重食源性致病菌联检方法研究,2025/01-2028/12,50万,主持
2. 国家自然科学基金青年项目,针对精准分析前列腺癌分期指示因子的超灵敏双极电极-多色电致化学发光法研究,2020/01-2022/12,26万,主持
3. 江苏省自然科学基金青年项目,双极电极-多色电致化学发光微分析系统的构建及其对前列腺癌分期研究,2019/09-2022/09,20万,主持
4. 2019年 江苏省“双创博士”(世界名校类)项目,15万,主持
5. 南京大学生命分析化学国家重点实验室开放研究基金项目,电位调控的多色电致化学发光研究与生物传感应用,2019/03-2021/03,5万,主持
6. 国家自然科学基金青年项目,21605079,多巴胺能神经元网络化学信息传递过程的时空分辨监测,2017/01-2019/12,20万元,参与
主讲课程
轻工科技前沿;生物分析化学;色谱与波谱学;胶体与界面化学;科研综合实训
代表性成果
(1) Yin-Zhu Wang, Ling-Ling Wang, Yan Liu, Yu-Qi Zhang, Meng-Li Li, Chuan-Xiang Chen*, Jia-Wan Zhu, Fu Yang, Yong-Hong Hu*. Dual “on-off” signal conversion strategy based on surface plasmon coupling and resonance energy transfer for visual electrochemiluminescence ratiometric analysis of MiRNA-141. Biosensors and Bioelectronics, 2024,253, 116162.(一区,IF=12.6)
(2) Yin-Zhu Wang*, Yu-Qi Zhang, Yan Liu, Yue-Rong Li, Meng-Li Li, Gong-Rui Meng, Li Mi, Yong-Hong Hu*, and Jing-Juan Xu*. A tripedal DNA walker as signal amplifier combined with potential-resolved multicolor electrochemiluminescence strategy for ultrasensitive detection of prostate cancer staging indicators. Analytical Chemistry, 2024, 96, 5852−5859. (一区,IF=7.4)
(3) Yin-Zhu Wang*, Yue-Rong Li#(本科生), Yu-Qi Zhang#, Yuan-Meng Xiang, Rong-Rui Bai, Yan Liu, Meng-Li Li, Gong-Rui Meng, Shun-Long Pan, Fang Zhang, Li Mi, and Yong-Hong Hu*. Dual-signal ratiometric electrochemiluminescence biosensor based on Au NPs-induced low-potential emission of PFO Pdots and LSPR-ECL mechanism for ultra-sensitive detection of microRNA-141. Biosensors and Bioelectronics, 2024, 261, 116495.
(4) Meng-Li Li , Ming-Yu Zhong , Jia Zhang, Yi-Jia Zhang, Yu-Qi Zhang, Yan Liu, XiangKai Li, Shu-Tian Gan, Gong-Rui Meng, Li Mi, Yong-Hong Hu, Fang Zhang, Xiao-Xu Zhang, Yin-Zhu Wang*. An “off-on-enhanced on” electrochemiluminescence biosensor based on resonance energy transfer and surface plasmon coupled 3D DNA walker for ultra-sensitive detection of microRNA-21. Analytica Chimica Acta, 2024, 1315, 342822. (二区,IF=5.7)
(5) Gong-Rui Meng(本科生), Shuang-Hong Yan, Meng-Li Li, Jun-Qian Liu, Chen-Xi Shi, Jia-Qi Ji, Ming-Yu Zhong, Jia Zhang, Yi-Jia Zhang, Yu-Qi Zhang, Yan Liu, Xiang-Kai Li, Shu-Tian Gan, Fang Zhang, Yong-Hong Hu and Yin-Zhu Wang*. An “on-off” ratiometric electrochemiluminescence biosensor based on LSPR-enhanced by Ag@Au nanostructures combined with Pd NCs catalysing a single luminophore for MiRNA let-7a detection. Sensors and Actuators B: Chemical, Accept. (一区,IF=8.0)
(6) Jie Zhao, Chuan-xiang Chen*, Jia-wan Zhu, Hui-long Zong, Yong-hong Hu*, Yin-zhu Wang*. Ultra-sensitive and visual electrochemiluminescence ratiometry based on constant resistor integrated bipolar electrode for microRNA detection. Analytical Chemistry, 2022, 94(10), 4303-4310.
(7) Xue yun Yang, Yin zhu Wang*, Ling ling Wang, Hui long Zong, Chuan xiang Chen*. Bipolar electrode ratiometric electrochemiluminescence biosensing analysis based on boron nitride quantum dots and biological release system. Biosensors and Bioelectronics, 2021, 191, 113393.
(8) Yan Liu, Jia Zhang, Jia-Wan Zhu, Yi-Jia Zhang, Ming-Yu Zhong, Xiang-Kai Li1, Shu-Tian Gan, Xue Han, Meng-Li Li, Ming-Zhu Deng, Yu-Qi Zhang, Gong-Rui Meng, Yang Wang, Li Mi, Zheng Xu, Meng Yang and Yin-Zhu Wang*. Electrochemiluminescence mechanisms and bioanalysis based on multi-shape gold nanoparticles and ATT-Au NC. Biosensors and Bioelectronics, 2021, 191, 113393. under review.
(9) Yin-Zhu Wang, Si-Yuan Ji, Heng-Yu Xu, Wei Zhao*, Hong-Yuan Chen, and Jing-Juan Xu*. Electrochemiluminescence bidirectional color switch: An application in accurate diagnosis of prostate cancer. Analytical Chemistry, 2018, 90 (5), 3570-3575.(Editor’s choice paper)
(10) Yin-Zhu Wang, Cong-Hui Xu, Wei Zhao*, Qi-Yuan Guan, Hong-Yuan Chen, and Jing-Juan Xu*. Bipolar Electrode Based Multicolor Electrochemiluminescence Biosensor. Analytical Chemistry, 2017,89, 8050-8056.
(11) Yin-Zhu Wang, Nan Hao, Qiu-Mei Feng ,Hai-Wei Shi, Jing-Juan Xu*, Hong-Yuan Chen. A ratiometric electrochemiluminescence detection for cancer cells using g-C3N4 nanosheets and Ag–PAMAM–luminol nanocomposites. Biosensors and Bioelectronics, 2016, 77, 76-82.
(12) Yin-Zhu Wang, Wei Zhao, Pan-Pan Dai, Hai-Jie Lu, Jing-Juan Xu*, Jing Pan, Hong-Yuan Chen. Spatial-resolved electrochemiluminescence ratiometry based on bipolar electrode for bioanalysis. Biosensors and Bioelectronics, 2016, 86, 683-689
(13) Huai-Rong Zhang, Yin-Zhu Wang (共同一作), Wei Zhao*, Jing-Juan Xu*, and Hong-Yuan Chen. Visual Color-Switch Electrochemiluminescence Biosensing of Cancer Cell Based on Multichannel Bipolar Electrode Chip. Analytical Chemistry, 2016, 88, 2884-2890. (一区,IF=6.986)
(14) Huai-Rong Zhang, Yin-Zhu Wang, Mei-Sheng Wu, Hai-Wei Shi, Hong-Yuan Chen and Jing-Juan Xu*. Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol. Chemical Communications, 2014, 50, 12575-12577 (一区,IF=6.222)
(15) 朱家万,陈传祥,王银珠. 基于金纳米簇电致化学发光猝灭传感器的制备方法及其应用。中国 专利,申请号:202310283773.4(已受理).
(16) 王银珠,刘彦,李孟丽,张玉琪,胡永红. 浅谈前沿科技成果在食品分析课程中的几点建议. 中国食品. 2024 年第 10月期.
培养研究生获奖情况:
1. 赵婕:2022届校优秀硕士毕业论文;
2. 朱家万:《多信号电致化学发光用于生物检测》,2021年江苏省科研创新计划,立项,已结题;
3. 刘彦:《以胸腺苷为载体的金纳米簇的合成与电化学发光研究》,2024年江苏省科研创新计划,立项,主持;
4. 张玉琪:《基于PDAcp NPs和适体结合的电化学发光生物传感器研究》,2024年江苏省科研创新计划,立项,主持
培养本科生获奖情况:
1. 李玥蓉:《基于PFO和掺硫氮化硼量子点的双信号比率型电化学发光生物传感器超灵敏检测micro-RNA》,2022年江苏省大学生创新创业训练计划项目,立项,已结题;获南京工业大学生物与制药工程学院本科生科技论坛特等奖;去向:华东理工大学;
2. 范怡:2022级生工专业本科毕业生,去向:华南师范大学;
3. 蒙恭芮:《基于双ECL信号发光材料的比率型电化学发光生物传感器检测micro-RNA》2023年国家级大学生创新创业训练计划项目,立项,主持;
4. 蒙恭芮:《其迹在“腺”》荣获2023年“南工劝业杯”南京工业大学“互联网+”大学生创新创业大赛暨第五届“创贏鼓楼”创新创业大赛、第三届“英才汇聚创贏鼓楼”青年大学生创新创业大賽选拔赛“高教主赛道-本科生创意组”优秀奖;去向:保送南京大学;
5. 邓逐流:2024级轻化工程专业本科毕业生,去向:华南理工大学。