周 谦
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  • 发布时间:2026-03-28
  • 更新时间:2026-03-28


个人简介:

女,博士学位,研究员。曾于江苏省中医药研究院从事心脑血管药理学研究,现为南京工业大学食品与轻工学院教师、硕士生导师江苏省第六期333高层次人才培养工程中青年科学技术带头人,兼任Frontiers in pharmacology客座编委以及ExplorationChinese Medicine等期刊青年编委。


研究方向:

中药药理、药食同源活性成分作用机理


联系方式

办公地点:材料化学国家重点实验室(弘毅楼C409

邮箱:njzhouqian@njucm.edu.cn


工作经历

1. 2025/04至今南京工业大学食品与轻工学院研究员

2. 2025/01-2025/03苏省中医药研究院心血管科研究员

3. 2019/01-2024/12江苏省中医药研究院心血管科副研究员

4. 2014/08-2018/12江苏省中医药研究院心血管科助理研究员


教育经历

1. 2011/09-2014/07南京师范大学生物化学与分子生物学博士

2. 2009/09-2011/07南京师范大学生理学硕士

3. 2005/09-2009/07南京师范大学生物技术学士


科研项目

1.2023/12-2026/12中草药表面活性剂的研发与应用(H2023010)企事业合作90主持

2. 2023/12-2026/12抗病毒感染性疾病中药的筛选与药效物质基础研究国家重点研发计划1785万元项目骨干

3.2022/01-2024/12心房肌NOX2-ROS调节Kv1.5/IKur信号通路的炙甘草汤治疗房颤分子机制及临床疗效研究(ZT202109)江苏省中医药科技发展项目45主持

4.2020/12-2022/11以电压门控Kv1.5/IKur通道为靶标寻找特异性治疗房颤的动物毒素及疗效研究(2020YLXK024)南京中医药大学20主持

5.2017/01-2019/12栀子苷干预ROS介导mTORC1-Nrf2信号通路防治帕金森病发生分子机理研究(81603332)国家自然科学基金青年基金18主持

6.2016/07-2019/06栀子苷干预ROS介导mTOR-Nrf2信号通路防治帕金森病发生分子机理研究(BK20161082)江苏省自然科学基金青年基金20主持


人才项目

周谦江苏省第六期333高层次人才培养工程中青年科学技术带头人2022/01-2026/12


科研荣誉

周谦1/7),2024-MZYY-96,马齿苋功效物质的发现及其功能和应用研究,中国民族医药协会科学技术进步二等奖2024


论文情况

1.Zhou Q#, Hao G#, Xie W, Chen B, Lu W, Wang G, Zhong R, Chen J, Ye J, Shen J, Cao P. Exenatide reduces atrial fibrillation susceptibility by inhibiting hKv1.5 and hNav1.5 channels. J Biol Chem 2024, 300(5): 107294.

2. Qin Y, Wang J, Chen R, Tang Z, Zhi H, Wu X, Chen X, Fu J, Cai X, Shen J*, Cao P*, Zhou Q*. Honey-fried licorice decoction ameliorates atrial fibrillation susceptibility by inhibiting the NOX2-ROS-TGF-β1 pathway. Front Pharmacol 2025, 16: 1595111.

3. Chen B, Sun S, Fu J, Ge L, Nie W, Zhou P*, Cao P*, Zhou Q*. Ethanol extract of Portulaca oleracea L. mitigates atherosclerosis through modulation of cholesterol efflux and uptake pathways. Frontiers in pharmacology 2025, 16: 1550812.

4. Shi J, Zhu XY, Yu RH, Liu WX, Yang J, Tang L, Kong CY, Luo HQ, Chen F, Xie WS, Fu JL, Wang JJ, Zhou Q*, Zhou Q*, Wang DJ*. Decreased METTL3 in atrial myocytes promotes atrial fibrillation. Europace. 2025 Feb 5;27(2):euaf021.

5.Lu J#, Zhou Q#, Zhu D#, Song H, Xie G, Zhao X, Huang Y, Cao P, Wang J, Shen X. Drofenine as a Kv2.1 inhibitor alleviated AD-like pathology in mice through Aβ/Kv2.1/microglial NLRP3/neuronal Tau axis. Acta Pharm Sin B. 2025 Jan;15(1):371-391.

6.Ma Y, Xu X, Mao S, Wang R, Gu Y, Qiu Y, Sun L, Xu H, Zhou Q*, Lei P*. Freeze-denaturation mitigation in surimi by Naematelia aurantialba polysaccharides: structural stabilization and ice recrystallization inhibition. Int J Biol Macromol 2025, 330(Pt 3): 148084.

7.Xu J, Hu H, Qian X, Zhang D, Chen G, Zhang F, Huang X, Ma S, Chen B*, Zhou Q*, Chen G*. Therapeutic effects of chamomile volatile oil nanoemulsion/Bletilla striata polysaccharides gels on atopic dermatitis. Int J Biol Macromol 2024, 277(Pt 4): 134404.

8.Zhou Q#, Chen B#, Xu Y#, Wang Y, He Z, Cai X, Qin Y, Ye J, Yang Y, Shen J, Cao P. Geniposide protects against neurotoxicity in mouse models of rotenone-induced Parkinson's disease involving the mTOR and Nrf2 pathways. J Ethnopharmacol 2024, 318(Pt A): 116914.

9.Shen Y, Wang X, Shen X, Wang Y, Wang S, Zhang Y, Yao X, Xu Y, Sang M, Pan J, Qin Y, Zhou Q*, Shen J*. Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis. Front Pharmacol 2022, 13: 879870.

10.Shen Y, Shen X, Wang S, Zhang Y, Wang Y, Ding Y, Shen J, Zhao J, Qin H, Xu Y, Zhou Q*, Wang X*, Shen J*. Protective effects of Salvianolic acid B on rat ferroptosis in myocardial infarction through upregulating the Nrf2 signaling pathway. Int Immunopharmacol 2022, 112: 109257.

11.Shen Y, Wang S, Liu Y, Ge L, Xia L, Zhang X, Miao Y, Shen J*, Zhou Q*. The Effects of Salvianolate Combined With Western Medicine on Diabetic Nephropathy: A Systematic Review and Meta-Analysis. Front Pharmacol 2020, 11: 851.

12.Zhou Q, Chen B, Wang X, Wu L, Yang Y, Cheng X, Hu Z, Cai X, Yang J, Sun X, Lu W, Yan H, Chen J, Ye J, Shen J, Cao P. Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways. Sci Rep 2016, 6: 32206.

13.Zhou Q#, Liu C#, Liu W#, Zhang H, Zhang R, Liu J, Zhang J, Xu C, Liu L, Huang S, Chen L. Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis. Toxicol Sci 2015, 143(1): 81-96.